Reduced phosphorous uptake results in decreased serum hyperphosphatemia - known to cause increased renal mineralization
DESCRIPTION:
Epakitin is a chitosan-based nutritional supplement that operates in the intestines. Chitosan is a natural polysaccharide extracted from crab and shrimp shells. In clinical trials, Epakitin has been proven effective as a phosphate binder, decreasing phosphatemia., In addition, chitosan was shown to reduce urea and creatinine levels in the blood.
METHOD OF ACTION:
- Decreases phosphorous absorption
- Reduces urea
- Reduces creatinine
- Reduces calcium absorption
- Increases life expectancy without affecting food consumption
- Effective with or without renal diet
FORMULATION(S):
- Demonstrated clinical efficacy
- Safe to use
- Highly palatable powder in three sizes
- Compatible with other therapies
- Easy and convenient to use for improved compliance
DOSING AND TREATMENT:
Epakitin should be recommended at the first signs of hyper-phosphatemia in cases of CKD. For best results, it is suggested to use Epakitin in combination with a low phosphorous diet. However, Epakitin’s highly palatable formulation can be used with regular food in animals that refuse to change their diet. Epakitin should be administered at the rate of 1 scoop (provided) per 10 lbs (5 kg) of body weight, twice daily, with food. The measuring scoop supplied delivers 1g of Epakitin. Fresh water should always be available for the animal.
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References:
- Survival of cats with naturally occurring chronic renal failure: effect of dietary management. J. Elliott, J.M. Rawlings, P.J. Markwell, P.J. Barber, JSAP (2000),
41, 235-242. - Effects of a dietary chitosan and calcium supplement on Ca and Premetabolism in cats.
E. Wagner, I. Schwendenwein, J. Zentek, Beri Munch. Tierarzta, Wschr.
(2004) 117, 310-315. - Effects of an intestinal phosphorous binder on serum phosphorous and parathyroid hormone concentration in cats with reduced renal function. S. A. Brown, M. Rickertsen, S. Sheldon, The Journal of Applied Research in Veterinary Medicine.
(2008) 6:3; 155-160.
