The benefits of SAMe plus improved
palatability and scored tablets for enhanced
dosing compliance.
DESCRIPTION:
Zentonil Plus, with SAMe, promotes healthy liver function with a new scored tablet and exclusive new microencapsulation technology that ensures optimal absorption of SAMe. This highly palatable formulation provides comphrehensive hepatoprotection in acute or chronic cases. Zentonil Plus can be used in all cases where the liver requires support in both dogs and cats. Ideal in subclinical or mild liver disease and regular administration of potentially hepatoxic drugs (Phenobarbital, NSAIDs, glucocorticoids, etc.)
METHOD OF ACTION:
- Maintains gluthathione levels
- Maintains membrane integrity
- Plays a role in protein synthesis
- Aids in hepatocellular regeneration
- Reduces pathological effect of certain inflammatory cytokines
- Plays a vital role in production of neurotransmitters
- May play a role in supportive care in cases of
cognitive decline
FORMULATION(S):
- Exclusive, new microencapsulation technology
- SAMe particles are encapsulated before being formed
into a tablet - Palatable tablets can be split, crushed or chewed for easier administration and accurate dosing
- Easy-to-administer to help increase compliance
- Proven palatability
- Rapid, proven bioavailability
- SAMe is available for use by the body within
10 minutes of administration - Peak levels are achieved between 1 to 4 hours
after administration - Effective with or without food (Optimal results on
an empty stomach) - Available in three convenient sizes (100, 200 and 400 mg)
DOSING AND TREATMENT:
Tablets are scored for easy division into two parts but can be divided further if required.
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References:
- Mischoulon D, et al. Role of S-adenosyl-L-methionine in the treatment of depression: a review of the evidence. Am J Clin Nutr 2002:76(suppl):1158S-61S.
- Alpert J E, et al. One-carbon metabolism and the treatment of depression: roles of S-adenosyl-L-methionine and folate. Chapter 5: Natural Medications for Psychiatric Disorders: Considering the Alternatives 2nd ed. Lippincott Williams & Wilkins, 2008.
- Data on file.
